Human Health

Next-Generation Molecular Diagnostics for Everyday Screening to Emerging Threats

Meet the next generation of molecular diagnostics. Avicena Sentinel supports everything from routine screening to outbreak response, empowering health providers to deliver unmatched screening services with speed at any scale.

The Rising Threat of Infectious Disease

In an increasingly connected world, the risk of infectious disease transmission remains a global concern.

Timely and accessible pathogen screening plays a critical role in supporting public health responses. Screening systems need to provide accurate, scalable, and efficient diagnostic results to enable informed decision-making and early intervention.

Diagnostic Solution

The Avicena Sentinel Platform

At the core of Human Health Screening Solutions is the Sentinel system – a next-generation diagnostics platform that delivers unmatched speed, accuracy, and flexibility for detecting human pathogens.
  • High-throughput capacity: From 10 to 384 [Sentinel Mini] or 5,000 tests/hour [Sentinel ULTRA] per instrumenta
  • PCR-comparable accuracy with results in 30 minutes
  • Flexible, non-invasive sample collection in under 20 seconds
  • Seamless integration with LIM systems and secure cloud platforms
  • Versatile deployment across labs, aged care homes, remote clinics, and mobile units

a. Dewhurst, R.E., Heinrich, T., Watt, P. et al. Validation of a rapid, saliva-based, and ultra-sensitive SARS-CoV-2 screening system for pandemic-scale infection surveillance. Sci Rep 12, 5936 (2022). https://doi.org/10.1038/s41598-022-08263-4.

Key Benefits

Fast, Scalable Results

Get accurate results in under 30 minutes with a throughput of 10 to 5,000 tests per hour. Continuously loaded, no batching.

Reliable Everyday Performance

Built for routine screening with high accuracy, low maintenance, and minimal manual handling, even in high-volume settings.

Flexible Deployment for Any Setting

Designed for aged care, mobile response units, and remote communities. No cold chain or complex infrastructure.

Affordable Screening at Any Scale

Affordable per-test costs with smart stockpiling, reduced waste, and efficient use of consumables.

Effortless Sample Collection

Sentinel platforms support a wide range of sample types, including saliva, nasal, blood, and skin lesions – delivering adaptable screening across human and animal screening contexts.

Each sample is collected in a barcoded tube pre-filled with stabilising buffer, enabling secure, end-to-end tracking from collection to result.

Pictured: Avicena’s custom-designed saliva/nasal swab for supervised, self-collection, captures the optimal volume for accurate, high-yield testing.

Applications

Aged Care

Vulnerable people in aged care require consistent infection surveillance to prevent outbreaks of influenza, COVID-19, and antibiotic-resistant bacteria.

Sentinel enables regular screening with minimal disruption, protecting residents, staff and the community.

Festivals & Pilgrimages

Large gatherings introduce infectious diseases into the population, with healthcare burdened by their ideal environment for spread.

Sentinel enables event organisers and public health agencies to screen attendees quickly and affordably, ensuring safer mass participation at religious pilgrimages, concerts, and sporting events.

Mobilise rapidly and integrate with the ticketing or identification system to stand up an end-to-end system in weeks.

Human Pathology

Clinical labs and health authorities benefit from Sentinel’s fast turnaround and scalable testing capacity, with PCR-level accuracy and real-time results.

Ideal for respiratory panels, highly transmissible community diseases, tropical diseases, or emerging pathogens in public health programs.

Food Safety & Manufacturing

Food production environments are vulnerable to microbial contamination, putting consumer safety and supply chains at risk. Routine screening of both food samples and the workforce helps prevent outbreaks and ensures compliance with health and safety standards.

Delays in test results often force food producers to store goods on-site, which drives up storage costs and compromises product freshness.

With Sentinel, results can be delivered onsite in as little as 30 minutes, eliminating week-long wait times associated with external lab testing.

Remote Outbreaks

From Indigenous communities to disaster zones and rural regions, Sentinel enables rapid deployments, delivering accurate diagnostics without the need for centralised laboratories.

Designed for mobility and simplicity, Sentinel empowers field teams to detect and contain outbreaks early, wherever they occur.

The system supports GPS-enabled sample tracking for real-time geomapping of outbreak spread, helping public health teams respond faster and smarter. Sentinel units can be mounted in utility vehicles or airlifted to remote locations, enabling flexible deployment in dynamic environments.

Upgrade your Diagnostic Strategy

Bring fast, scalable, and affordable molecular diagnostics to your health system.

Frequently Asked Questions

Standard Avicena instruments operate in an operating environment between 15 and 25 degrees Celsius, but deployment options typically include a van/cab or demountable building with built-in air conditioning supporting external environments from -20 to 50 degrees.

The samples and chemistry are stable between 0 and 25 C and are transported in portable coolers or insulated bags between sites.

Traditional PCR often requires batching, complex lab infrastructure, and long turnaround times. Avicena Sentinel delivers PCR-comparable accuracy with results in under 30 minutes. It is built for continuous, high-throughput screening with minimal manual handling — perfect for both routine and surge testing.

The platform supports a broad panel of infectious diseases including:

  • Respiratory viruses: COVID-19, Influenza A/B, RSV
  • Tropical diseases: Dengue, Zika, Malaria
  • Sexually transmitted infections
  • Tuberculosis and drug-resistant bacteria

Emerging pathogens can also be rapidly targeted using custom assays.

No, Sentinel supports non-invasive sample types like saliva and shallow nasal swabs, collected in under 20 seconds. This makes it ideal for frequent or mass screening in vulnerable populations like aged care residents or festival attendees.

Sentinel delivers real-time results in under 30 minutes, with testing throughput ranging from 10 to 5,000 tests per hour, depending on the model. It supports continuous flow testing without the delay of batch cycles.

Minimal infrastructure is needed. Sentinel instruments require no cold chain, are cloud-compatible, and can be used in remote or mobile units. This makes them ideal for rapid deployment in emergencies, underserved regions, or temporary testing stations.

Certifications

ISO 13485 certified for the design, development, and manufacture of in vitro diagnostics

CE-Marked for use in the in vitro diagnostic (IVD) molecular testing

Patent-Pending

Avicena holds several patent pending innovations that enable our groundbreaking performance.

Intended Use of the Avicena Sentinel instrument

The Avicena Sentinel instrument is intended for trained laboratory professionals to run human IVD isothermal amplification assays. Diagnostic use of the Sentinel requires IVD reagents and laboratory workflows which have been authorised by relevant regulatory agencies in each jurisdiction and by Avicena Systems as compatible with the instrument.

The Avicena Sentinel instruments are also available in configurations for research use, environmental/surveillance, animal health screening, and food safety testing.

AVICENA SENTINEL IS NOT AVAILABLE FOR PURCHASE BY THE GENERAL PUBLIC.

Avicena Sentinel is for in vitro diagnostic use in humans and animals.

Avicena Seguro is for animal health and research use only (RUO).

Contact an Avicena Systems representative for regional availability.